nobiletin相关论文
Objective Early placental development isoccurred in a relatively hypoxic environment and the physiological level of oxid......
Objective To identify the agonists for Neuromedin U 2 receptor by using NMU2R cell line which was established by cotrans......
Nobiletin is the important kind of natural product derived from tangerine or orange peel.And Nobiletin has kinds of phar......
AIM We have demonstrated for the first time that nobiletin (NB) from citrus peels improves memory impairment in Alzheime......
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergisti
Objective: Natural extracts, including nobiletin, have been reported to enhance the efficacy and sensitivity of chemothe......
建立了薄层色谱-高效液相色谱-四极杆飞行时间质谱法联用技术(TLC-HPLC-QTOF-M S)快速鉴定柑橘提取物消毒液中桔皮素、蜜橘黄素、......
,Nobiletin and its derivatives overcome multidrug resistance (MDR) in cancer: total synthesis and di
Our recent studies demonstrated that the natural product nobiletin (NOB) served as a promising multidrug resistance (MDR......
Nobiletin downregulates the SKP2-p21/p27-CDK2 axis to inhibit tumor progression and shows synergisti
Objective:Natural extracts,including nobiletin,have been reported to enhance the efficacy and sensitivity of chemotherap......
纳米结构脂质载体（nanostructured lipid carrier,NLC）是一种新型的纳米脂质载体,将其搭载活性物质已经广泛应用于食品的多个相关领......
以柑橘皮为原料，建立紫外分光光度测定方法，研究响应面优化双酶法提取川陈皮素的最佳工艺。利用紫外分光光度法测定柑橘皮中川陈皮素......
目的:观察诺必擂停体内外的抗肿瘤作用.方法:体内实验采用3种移植性肿瘤模型(S180、BGC-823、EAC),计算各用药组抑瘤率、EAC小鼠生......
研究了抗癌药物诺必擂停在玻碳电极上的电化学行为及其反应机理,建立了一种灵敏的测定诺必擂停的分析方法。实验结果表明,在pH 2.0......
目的：探讨川陈皮素诱导的A549细胞死亡方式。方法：40、80μg／ml的川陈皮素分别处理A549细胞12、24、46h后，用彗星电泳法来检测DNA的损......
目的：研究川陈皮素的化学全合成路线。方法：从基本的化工原料间苯二酚开始，经６步合成此化合物，即间苯二酚溴代，醚化，苯环上亲核取代，付科......
诺必擂停（nobiletin）是从芸香科植物橘及其栽培变种的果实中提取的一种类黄酮，化学命名为5，6，7，8，3’4’-六甲氧基黄酮（5，6，7，8，3’4’-hexamet......
本文制备了川陈皮素纳米乳（NOB-NE），考察了纳米乳载药前后的理化特性、稳定性及其在小鼠体内的分布情况。制得的川陈皮素纳米乳的粒径......
采用小鼠肺高转移黑色素瘤细胞K111尾静脉注射肺转移模型，研究川皮苷的抗肿瘤转移作用，并在体外试验中研究其对K111细胞分泌明胶酶MM......
目的研究诺必擂停（NOB）对小鼠肝癌移植瘤Heps的作用及其免疫学机制。方法建立小鼠肝癌移植瘤Heps实体型模型，解剖剥离肿瘤称重，计算抑......
测定了广西、广东新会、广州近郊、江西、湖南等5个陈皮主产地的陈皮油中3种多甲氧基黄酮（川陈皮素、七甲氧基黄酮、橘皮素）的含量及......
目的:研究诺必擂停在大鼠和Beagle犬体内的药动学过程。方法:通过口服和静注两种给药方式,用高效液相色谱法测定血浆中诺必擂停的......
川陈皮素(Nobiletin)是存在于柑橘皮中的一类多甲氧基黄酮(Polymethoxyflavones,PMFs),具有抗炎、抗肿瘤、改善肥胖和胰岛素抗性作......
Obesity and osteoporosis are associated with estrogen deficiency following menopause. Therefore, it is important to prev......
目的：建立川陈皮素PLGA纳米粒含量的高效液相色谱测定方法。方法采用反相高效液相色谱法。以ODS-C18（250 mm ＆#215;4．6 mm ，5μm）为分析......
Protective Effects of Nobiletin on Hypertension and Cerebral Thrombosis in Stroke-Prone Spontaneousl
Some citrus flavonoids have been reported to possess antioxidant activities that moderate endothelial dysfunction and sh......
OBJECTIVE Dysregulation of circadian rhythms is associated with metabolic dysfunction,yet it is unclear whether enhancin......
目的：测定中药陈皮中川陈皮素的含量。方法：采用ＲＰ－ＨＰＬＣ法、色谱条件为μ－ＢｏｎｄａｐａｋＣ１８柱，四氢呋喃－乙腈－甲醇－水为流动相，检测波长３２８ｎｍ，结果：不同批号陈皮药材中川陈......
